The aim of the study was to evaluate longitudinal associations between HbA1c levels, diabetes status and subsequent cognitive decline over a 10 year follow-up period. Cognitive function was assessed at baseline and reassessed every 2 years.
HbA1c was significantly associated with an increased rate of decline in global cognitive, memory and executive function. Similarly, memory, executive function and orientation showed an increased rate of cognitive decline with diabetes.
Future studies are required to determine the effects of maintaining optimal glucose control on the rate of cognitive decline in people with diabetes.