Ceaseless work, analysis, reflection, writing much, endless self-correction, that is my secret
Johann Sebastian Bach
I am happy to contribute to the editorial by Lisa Eramo published in Medical Economics, January 2018. The article is important as it raises physician awareness of Merit-based Incentive Payment System (MIPS) under which hypertension management falls. MIPS, part of 2015 MACRA, will go into effect in 2019.
This meta-analysis of four major clinical trials (ELIXA, LEADER, SUSTAIN 6, EXSCEL) reveals safety of GLP-1 agonists, bur more importantly their cardiovascular benefits on mortality, myocardial infarction and stroke in adults with type 2 diabetes.
The next natural step would be the quest for oral version of GLP-1 agonist given its positive profile on appetite, glucagon, insulin, glucose metabolism, proteinuria and cardiovascular system.
If ever a composer showed polyphony in all its great strength, it was surely Bach. Nobody has shown as much as he, in works which normally seem so dry, as much imagination and original thought.
His melodies were indeed unusual, but they were always varied, rich in invention, and they are not at all like those of other composers. His serious temperament drew him primarily towards elaborate music which was grave and profound.
It was only his personal reflections which made him, right from the youth, a composer of pure and powerful fugues.
Carl Philipp Emanuel